Constraint Based Alignment Editor with Automatic Alinger and Motif Dictionary Retriever

MAKOTO HlROSAWA[1] (hirosawa@sdl.hitachi.co.jp)
YASUSHI TOTOKI[2] (totoki@icot.or.jp)
MASATO ISHIKAWA[2] (ishikawa@icot.or.jp)

[1]ex-ICOT, presently with Hitachi System Development Laboratory
1099 Ohzenji, Asao, Kawasaki, Kanagawa 215 JAPAN
[2]Institute for New Generation Computer Technology (ICOT)
1-4-28 Mita, Minato, Tokyo 108 JAPAN


Abstract

We have developed an alignment editor for protein sequences and/or nucleotide sequences that runs under the on X-window system. The system is equipped with automatical aligner and motif dictionary. The system can iteratively identify known motifs stored in the motif dictionary and gradually improve the quality of the alignment to discover new motifs.