Kanehisa Laboratories

Fukuoka - Kyoto - Tokyo

KEGG MEDICUS

Thanks to the continuous developments of high-throughput experimental technologies since the Human Genome Project, it is now a routine task to determine the genome sequence of an organism or to obtain other types of large-scale molecular data such as metabolomics data. The KEGG resource has been developed as a reference knowledge base for understanding cellular and organism level functions from such data. It is being expanded to meet the needs of translational bioinformatics, helping the research community for translating research results into practical applications and helping society for better understanding of scientific basis of diseases and drugs.
Translational Bioinformatics
Role Example
Research
Community
Helping to translate genome-based research
results into practical applications
Personalized medicine
Society Helping to understand scientific basis of
diseases and drugs of personal interests
Participatory medicine


KEGG MEDICUS is partially supported by the Database Integration Coordination Program in the NBDC Program of the Japan Science and Technology Agency.

Title
Integrated database linking human and pathogen genomes to diseases and drugs
Period
2022.4 - 2026.3
Summary
We develop a new reference knowledge base named KEGG NETWORK for perturbed molecular networks involving human diseases and drugs. KEGG NETWORK is a collection of network variants, such as variants of signaling pathways, caused by gene variants and other factors. We also develop a network mapping tool for interpretation of personal genome sequences.